Case of the Month #56 The Protein Puzzle: A Case of Progressive Multi-Organ Dysfunction
What is amyloidosis and how is it classified?
Amyloidosis refers to a group of diseases characterized by the extracellular deposition of insoluble fibrillary proteins (amyloid) in various tissues and organs. Amyloid fibrils form when proteins misfold and aggregate into beta-pleated sheets.
Classification is based on the precursor protein that forms the amyloid fibrils: