Central nervous system
Impaired conscious level / coma
Slurring of speech
Irritability
Agitation
Seizures
Weakness
Lethargy
Dizziness
Cardiovascular
Tachycardia
Widened pulse pressure
Hypotension
Respiratory
Tachypnoea
Respiratory alkalosis
Gastrointestinal
Nausea / vomiting
Bleeding
Renal
Oliguria
Acute kidney injury
Myoglobinuria
Haematuria
Metabolic
Extremely elevated core body temperature
Rhabdomyolysis
Metabolic acidosis
Endocrine
Hypoglycaemia
Cutaneous
Dry, hot skin