What are the causes of Primary Adrenal Insufficiency?
Autoimmune adrenalitis – this is the most common cause in Western Countries and can be associated with syndromes such as Autoimmune Polyendocrine Syndrome type 1 and 2 (APS 1 and 2). Adrenal cortex autoantibodies or antibodies against 21-hydroxylase are present in more than 80% of people with recent-onset autoimmune adrenalitis.