Case of the Month #48 Nephrogenic DI

Published 25/04/2024

What do you know about the prognosis of Diabetes Insipidus?

The prognosis for most patients with diabetes insipidus is excellent as long as the underlying primary cause can be treated. 

Lithium discontinuation can restore normal kidney function, but the nephrogenic DI may be permanent in some patients.  

As long as the individual has access to water, mortality can be avoided. However, the condition can lead to cardiovascular collapse, fever, and hypernatremia in children and older patients.