Previously based on a mean pulmonary arterial pressure (mPAP) of ≥25 mmHg measured at right heart catheterisation.
The mPAP cut-off has been reduced to 20 mmHg in the presence of other haemodynamic characteristics. There are 3 haemodynamic definitions:
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Definitions
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Characteristics
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Pre-capillary PH
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mPAP >20 mmHg
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PAWP ≤15 mmHg
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PVR >2 WU
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Isolated post-capillary PH
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mPAP >20 mmHg
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PAWP >15 mmHg
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PVR ≤2 WU
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Combined pre- and post-capillary PH
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mPAP >20 mmHg
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PAWP >15 mmHg
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PVR >2 WU
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mPAP – mean pulmonary arterial pressure
PAWP – pulmonary arterial wedge pressure
WU – Wood units, a unit of pulmonary vascular resistance. 1 WU
= 80 dynes/s/cm-5
Gold standard for diagnosis is right heart catheterisation (RHC).
