Case of the Month #26 - liver failure

Published 10/02/2022

Key Take Home Messages

  • Paracetamol toxicity is a common cause of hepatic necrosis and failure, blood level > 250mg/kg can cause hepatic necrosis.
  • Patients with paracetamol induced hepatotoxicity should be discussed early with the regional liver centre.
  • Patients with severe liver failure are likely to need prompt resuscitation.
  • Avoid correction of coagulopathy unless the patient is actively bleeding.
  • There are criteria for determining if a patient should be considered for a liver transplant (for example the King’s College Criteria).