Case of the Month #53 AFLP

The prognosis of AFLP has improved significantly with advances in critical care and earlier recognition:

• Maternal mortality has decreased from 80-85% historically to 7-18% in recent years
• Fetal mortality rates have improved from 50% to 9-23%

Factors influencing outcomes include:

1. Time to diagnosis and delivery (if antenatal)
2. Severity of liver dysfunction and coagulopathy
3. Development of complications (e.g., sepsis, multi-organ failure)
4. Access to advanced critical care facilities
5. Presence of pre-existing medical conditions