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Antepartum   
- Placenta praevia 
- Placental abruption 
- Bleeding from genital tract (cervix, vagina or vulva) 
- Unknown 
Placenta praevia and placental abruption are the most important causes of APH. 
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Intrapartum   
- Placenta Praevia 
- Placental Abruption 
- Uterine rupture 
- Amniotic Fluid embolism 
- 
Postpartum - The 4 T’s  
- 
Tone- uterine atony/ abnormalities of uterine contraction (the most common cause of primary PPH- 80% of cases).   
- 
Tissue- retained products of conception e.g. placental tissue, or blood clots  
- 
Trauma- genital tract trauma i.e. lacerations of the cervix/ vagina/ external genitalia or perineum, extensions of uterine incisions at caesarean section, uterine rupture, uterine inversion  
- 
Thrombin- abnormalities of coagulation. These can be acquired in pregnancy e.g. gestational thrombocytopenia, pre-eclampsia with HELLP, sepsis, abruption, amniotic fluid embolus, existing e.g. Haemophilia A, von Willebrand disease, or due to therapeutic anticoagulation e.g. for a history of thromboembolic disease or cardiac valve replacement.  
Early risk assessment for obstetric haemorrhage of all pregnant women is essential. 
Steps to minimise the risk of MOH antenatally include-  
- 
Investigation and treatment of antenatal anaemia (consider iron supplementation for Hb <110 g/l at first contact or <105 g/l at 28 weeks).  
- 
Individualised PPH risk assessment of current and previous risk factors throughout the antenatal & intrapartum period.  
Risk factors for primary PPH (the most common cause of MOH) include: 
- 
Antenatal  
- 
Anaemia or bleeding disorder (Hb <95 g/L, platelets < 100 x 109/L)  
- 
Body Mass Index (BMI) < 18 or >35 or booking weight < 55kg  
- 
> 5 previous vaginal births  
- 
Previous PPH > 1000 ml  
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Perinatal  
- 
Suspicion of chorioamnionitis/ sepsis  
- 
Labour augmented with syntocinon  
- 
Prolonged labour  
- 
Instrumental delivery  
- 
Retained products of conception