There are many causes, but examples include:
Group
|
Examples
|
1. PAH
|
Idiopathic, heritable, connective tissue disease, drug and toxin-induced, portal hypertension, HIV
|
2. PH-LHD
|
Left ventricular systolic or diastolic impairment, valvular heart disease
|
3. PH-LD
|
Obstructive, restrictive, hypoxia without lung disease
|
4. PH due to pulmonary artery obstruction
|
Chronic thromboembolic PH (CTEPH)
|
5. PH with unclear / multifactorial mechanisms
|
Sarcoid, haematological, metabolic
|
PAH – pulmonary arterial hypertension
PH-LHD – PH due to left heart disease
PH-LD – PH due to lung disease