Case of the Month #58 From River to Resus: A Severe Case of Leptospirosis

Published 27/11/2025

How would you treat leptospirosis?

Specific treatment- Early administration of antibiotics e.g. IV ceftriaxone.  

Supportive management 

The use of steroids and plasma exchange have been described in some cases of severe disease although the evidence for this is low quality and more research is needed.