Case of the Month #41 Posterior Reversible Encephalopathy Syndrome (PRES)

Published 20/07/2023

What are the associated features of PRES? [1]

Hypertension and associations 

  • It is the rate of BP rise rather than the absolute pressure which is most of concern  

  • Pre-eclampsia and eclampsia 

  • Renal failure 

  • Guillain-Barre Syndrome (autonomic instability) 


Inflammation and endothelial dysfunction 

  • Sepsis 

  • Autoimmune disease 

  • Thrombotic microangiopathies 



  • Anything that can cause hypertension or endothelial damage 

  • Chemotherapeutics 

  • Anti-inflammatory 

  • Pro-inflammatory, VEGF-I, TKI  

  • Sympathomimetics 

  • Carbamazepine 

  • Lithium 

  • Linezolid