Case of the Month #41 Posterior Reversible Encephalopathy Syndrome (PRES)

Published 20/07/2023

What is the Prognosis?

  • As a general rule, patients with PRES make excellent recoveries 

  • Recovery can take several days 

  • For a rare few, the syndrome may progress to malignant PRES 

  • PRES can cause irreversible injury and patients may be left with long term neurological deficits  

  • Predictors of incomplete recovery: 

    • Secondary intracranial haemorrhage  
    • Restricted diffusion on MRI, suggestive of cerebral infarction 
    • Extensive cerebral oedema [7] 
  • Patients may have recurrent episodes of PRES, especially if they have a persistent risk factor  

  • 15% mortality [8]