Case of the Month #49 Hyperinflammatory State in the Intensive Care Unit

Published 23/05/2024

What other clinical tests are required from this patient to aid the diagnosis of HLH?

  • Lipid screen
  • Ferritin
  • Clotting screen
  • Bone marrow aspirate

Results

  • Triglycerides 4.3
  • Ferritin 12430
  • Fibrinogen 2.1

(Even without bone marrow aspirate the likelihood of HLH was 99%)

Bone marrow biopsy demonstrated haemophagocytosis