Case of the Month #49 Hyperinflammatory State in the Intensive Care Unit

• Lipid screen
• Ferritin
• Clotting screen
• Bone marrow aspirate

Results

• Triglycerides 4.3
• Ferritin 12430
• Fibrinogen 2.1

(Even without bone marrow aspirate the likelihood of HLH was 99%)

Bone marrow biopsy demonstrated haemophagocytosis